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Aciphex (Rabeprazole)

What is Aciphex?

By its generic name, rabeprazole, Aciphex is a drug used to treat gastric problems and gastroesophageal reflux syndrome (better known as GERD). This is possible by its mechanism of action as a proton pump inhibitor. How does this work? Is something you may be wondering?

In order to process food during the process of digestion, the stomach produces a certain quantity of acid to degrade different kinds of food (this process is controlled and regulated by enzymes on the body). However when there’s an excessive production of this acid caused by a medical condition, there’s a problem. Because acid not only degrades food but other structures, as an example of this, when there’s presence of reflux, esophageal walls are deeply affected by acid, leading to a lot of pain.

Aciphex then comes into action, blocking these enzymes on the stomach walls to stop the production of acid and give the affected structures, a chance to heal.

It is also taken with antibiotics to prevent gastric ulcers caused by infections with Helicobacter pylori.
It could also be used to protect the stomach when there’s a high consumption of oral treatments such as pills and capsules. You see, there’s always a chemical reaction in your stomach every time you take a medicine. There’s an increase in the amount of acid to degrade the components and, then, absorb. For that reason, this drug needs to control the quantity of acid, so it won’t affect other structures.

General Warnings:

Aciphex in pregnancy: Aciphex is not expected to harm an unborn baby. However do tell your doctor if you are pregnant or plan to become pregnant while using this medicine. Just in case.It is unknown whether rabeprazole passes through breast milk or if it could harm a child. Tell your doctor if you are breast-feeding a baby.

And please, do NOT give this medicine to a child without medical advice. Dosages and medical history of the patient are serious business.

Side effects of Aciphex

Note: Aciphex comes from a line of drugs with the same mechanism of action. These are the proton pump inhibitors. Some examples are: lansoprazole (Prevacid), esomeprazole (Nexium), omeprazole (Prilosec, Zegerid), or pantoprazole (Protonix). If you’re allergic to any of these, there’s a big possibility of you being allergic of Aciphex as well. If that’s the case, you should not take it.

Get emergency medical help if you have signs of an allergic reaction to Aciphex, some of them are: difficulty breathing; swelling of your face, lips, tongue, or throat.

Common side effects

Sore throat;
Stomach pain

Severe side effects

Please in case of any of these, stop taking the medication and call for medical help.
Severe stomach pain
Diarrhea that is watery or bloody
Kidney problems (blood in your urine or swelling)
Dizziness, confusion
Fast or uneven heart rate
Shaking or jerking muscle movements;
Muscle cramps or spasms in your hands and feet;
Choking feeling.


The information in this article should be taken as a good guide but it’s always a good idea to consult these things with your doctor.

The recommended dosage for adults is 20 mg on a daily tablet. Tablets should be swallowed whole regardless of food. ACIPHEX is usually indicated for short-term (not more than 8 weeks) treatment in the healing and relief of gastroesophageal reflux disease.

In children the period of treatment is a little longer because the effect is not immediate. Recommended dosage of ACIPHEX for pediatric patients from 1 to 11 years of age by body weight is:
>15 kg: 5 mg once daily for up to 12 weeks with the option to increase to 10 mg if there’s no good response
<15 kg or more: a capsule of 10 mg daily for 12 weeks. Do follow all directions on the prescription and medicine package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. All the information is useful. It’s important for a doctor to know your case first, in order to give an accurate treatment to your health problems.

Missed Dose

Take it as soon as you remember. Skip it if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.


In case of overdose, call emergency help as soon as possible.