Stroke, and other heart-related complications. Lipitor can also raise the levels of HDL cholesterol (“good “cholesterol) in your blood. A generic version of Lipitor atorvastatin, approved by the FDA The drug is sometimes prescribed for people with an existing heart condition to lower their risk of experiencing a heart attack or other cardiac event. Additionally, Lipitor may be prescribed as a preventive drug for people with type 2 diabetes, high blood pressure (hypertension), a history of smoking, or other conditions that could increase their risk for heart complications. In 2014, the company denied liability for lawsuits by women who claimed that Lipitor gave them type 2 diabetes, stating that the women may have other risk factors that make them vulnerable to the disease, such as high blood pressure or obesity.
Individuals bring Lipitor with the trust of supporting a sound way of life and not with creating diabetes. In any case, as per a 2012 cautioning by the U.S. Nourishment and Drug Administration (FDA), some cholesterol-decreasing statins, including Lipitor, may build the dangers of lifted glucose levels and creating sort two diabetes. The FDA requested Pfizer, the producer of Lipitor, to add notices about diabetes dangers to Lipitor’s marks.
The lawsuits follow a 2012 call by the FDA to change the labeling of the drug to include a warning about the drug’s link to high blood sugar and increased risk for type 2 diabetes.
In a study of more than 470,000 patients newly treated with a statin, researchers found that Lipitor presented the highest diabetes risk. Additional studies reported that diabetes risk is higher for certain groups, including the elderly, women, and Asians.
Lipitor (atorvastatin) and Crestor (rosuvastatin) both effectively cleared away about 1% of artery-clogging plaque in heart patients after two years. Both drugs also lowered LDL, or “bad” cholesterol, and raised patients’ good HDL levels.
Crestor, and Lipitor, work in basically the same way. They reduce the amount of cholesterol made by the liver. Both Crestor and Lipitor are meant to work along with a healthy, low-cholesterol diet. Lowering LDL and triglycerides and raising HDL in the blood reduces the risk of heart disease, stroke and heart attack.
Lipitor and other statins indicates these drugs can increase a patient’s risk for developing diabetes, they shed little light on how the increased risk occurs. Type 2 diabetes occurs when the body fails to properly use or produce insulin, a crucial hormone the body uses to convert food into energy.
Lipitor can cause serious side effects. Stop taking the drug and call your doctor right away if you have any of these serious side effects:
Unexplained muscle pain, tenderness, or weakness, Confusion, memory problems, or other cognitive issues, Fever, unusual tiredness, and dark colored urine Swelling, weight gain, urinating less than usual or not at all Increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss, Nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
Less serious side effects from Lipitor may include mild muscle pain, diarrhea, or mild nausea.
Lipitor can be administered as a single dose at any time of the day, with or without food.
The dosage range of Lipitor is 10 to 80 milligrams (mg) once daily, and it is usually given as a 10 or 20 mg once daily. However, depending on your condition and medical history, you may be prescribed 40 mg once a day.
If you or someone else takes too much Lipitor, go to an emergency medical facility right away.
If you miss a dose of Lipitor, take it as soon as you remember unless it has been more than 12 hours since you missed your last dose.
In this case, wait and take the next dose at your regular time. Do not take two doses of Lipitor at the same time.
For primary prevention, atorvastatin treatment was effective in hypertensive patients with normal or mildly elevated cholesterol levels as well as in patients with type II diabetes. Patients had relatively low cholesterol levels at baseline in both trials; however, treatment with atorvastatin still resulted in significant reductions in cardiovascular outcomes and stroke.
For secondary prevention, intensive lipid-lowering therapy with atorvastatin 80 mg/day was associated with the significant incremental clinical benefit beyond therapy with 10 mg/day in patients with stable coronary heart disease. It was also shown to significantly reduce the risk of clinical outcomes in coronary heart disease patients versus usual medical care.